Of Mice and Men is the movie JM played a mentally handicapped man in.

I'm not in anyway trying to debunk the statements the guest made, I just want to highlight some confusion in the statement regarding the moment in the John Malkovich movie. The guest makes the statement there wasn't a movie in which John Malkovich played a retarded man (for lack of a better term). Evidently in Being JM, John Malkovich is being heckled by someone saying they like retarded guy he played in one of his films. The guest makes the comments JM never played a character like that in any film. But he did. He played a mentally handicapped man in Of Mice and Men, starring JM and Gary Sinise.